Mitragyna speciosa (Kratom) is a plant indigenous to some parts of Asia. The alkaloids were found in trace amounts in the very young leaves. People who use kratom regularly and then stop taking it may experience decreased appetite, diarrhea, muscle pain and spasms, twitches, watery eyes, anxiety, trouble sleeping, anger, hot flashes, and fever.

Yamamoto, L. T., Horie, S., Takayama, H. et al. (1999), ‘Opioid receptor agonistic characteristics of mitragynine pseudoindoxyl in comparison with mitragynine derived from Thai medicinal plant Mitragyna speciosa', General Pharmacology, Volume 33, pp. 73-81.

kratom seeds for sale users, in general, claimed they felt elated, strong, and active after using or consuming it (Suwanlert, 1975 ). Vicknasingam et al. ( 2010 ) record that users of ketum reported increased work capacity, heightened sexual desire, and increased levels of physical activity.

Harizal, S. N., Mansor, S. M., Hasnan, J., Tharakan, J. K. J., and Abdullah, J. (2010), ‘Acute toxicity study of the standardized methanolic extract of Mitragyna speciosa Korth in rodent', Journal of Ethnopharmacology, Volume 131, pp. 404-409. The main psychoactive components in the leaves are mitragynine and 7-hydroxymitragynine, both found only in Mitragyna speciosa.

Several botanical products can be used for recreational purposes, and the effects include changes in mood, perception, behavior, and even in physiological parameters 1 Although consumers usually have the wrong idea that they are completely safe and consumption does not involve any social or health risks, it is important to note that evidence of toxicity of such products has already been reported 2 , 3 Commonly, the consumption of certain plants is associated with specific locations where people use them for what it seems to be the natural effects" of the plant compounds.
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